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Police are appealing for witnesses following a collision in Hillingdon.
Police were called by London Ambulance Service at 19:03hrs on Monday, 26 January to Stanwell Moor Road, West Drayton following reports of a motorcycle in collision with a car.
The rider, aged in his mid-30s, was taken to a central London hospital where his condition is described as critical.
The driver stopped at the scene.
Detectives from the Serious Collision Investigation Unit at Alperton are investigating.
At this early stage, it is believed that the motorcycle was travelling northbound before crossing the central reservation. The road would have been busy at that time of day.
Anyone who witnessed the collision or the moments leading up to it is asked to contact the witness appeal line on 020 8991 9555.
Enquiries continue. No arrests.